eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| well-differentiated liposarcoma | ||||
| Disease ID | 1450 |
|---|---|
| Disease | well-differentiated liposarcoma |
| Definition | A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation. |
| Synonym | liposarcoma - differentiated liposarcoma - well differentiated liposarcoma, differentiated liposarcoma, well differentiated liposarcoma, well differentiated (morphologic abnormality) well differentiated liposarcoma of deep soft tissue |
| Orphanet | |
| DOID | |
| UMLS | C1370889 |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:6) C0023827 | liposarcomas | 2 C0023827 | liposarcoma | 2 C0206644 | fibrous histiocytoma | 1 C0334463 | malignant fibrous histiocytoma | 1 C1509147 | histiocytoma | 1 C0023798 | lipoma | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:3) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | Symbol | Locus(Total Locus:3) |
| Disease ID | 1450 |
|---|---|
| Disease | well-differentiated liposarcoma |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:3) HP:0012211 | Abnormal renal physiology HP:0001482 | Subcutaneous nodule HP:0002579 | Gastrointestinal dysmotility |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0002664 | Neoplasia | 2 HP:0012034 | Liposarcoma | 2 HP:0012032 | Lipoma | 1 HP:0012315 | Histiocytoma | 1 HP:0001289 | Confusion | 1 |
| Disease ID | 1450 |
|---|---|
| Disease | well-differentiated liposarcoma |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0012211 | Abnormal renal physiology | MP:0011682 | renal glomerulus cysts | abnormal membranous sacs in any portion of the renal glomerulus |
Mapped by homologous gene(Total Items:3) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0012211 | Abnormal renal physiology | MP:0014074 | increased brain glycogen level | greater than the normal concentration of a readily converted carbohydrate reserve in brain |
| HP:0002579 | Gastrointestinal dysmotility | MP:0013659 | abnormal erythroid lineage cell morphology | any structural anomaly of an immature or mature cell in the lineage leading to and including erythrocytes |
| HP:0001482 | Subcutaneous nodule | MP:0013542 | abnormal submandibular gland branching morphogenesis | |
| Disease ID | 1450 |
|---|---|
| Disease | well-differentiated liposarcoma |
| Case | (Waiting for update.) |